Clinical research reduced by 87% at peak of pandemic – UCL
At the peak of the COVID-19 pandemic, clinical research capacity may have been reduced by up to 87% in England, finds a new study led by UCL academics. In the study, published in PLOS One, researchers estimated that at a population infection rate of 10% – at the peak in April, for over a month […]
Encouraging results from trial of inhaled drug – University of Southampton
The University of Southampton and drug-development-company Synairgen plc have announced positive results from clinical trials of a drug (SNG001 – inhaled formulation of interferon beta) that may prevent worsening of COVID-19 in those most at risk. The odds of developing severe disease (e.g. requiring ventilation or resulting in death) during the treatment period (day 1 […]
Statisticians help in search for effective COVID-19 treatments – Lancaster University
Statisticians from Lancaster University are involved in an innovative new COVID 19 drug testing platform. Launched this week, the AGILE initiative, is a collaboration between the Universities of Liverpool, Southampton, Lancaster and Liverpool School of Tropical Medicine, as well as external partners. AGILE has been developed by Infectious Diseases clinicians, clinical and pre-clinical pharmacologists, clinical […]
Anti-inflammatory drug found to reduce deaths in COVID-19 patients – University of Oxford
In March 2020, the RECOVERY (Randomised Evaluation of COVid-19 thERapY) trial was established as a randomised clinical trial to test a range of potential treatments for COVID-19, including low-dose dexamethasone (a steroid treatment). Over 11,500 patients have been enrolled from over 175 NHS hospitals in the UK. On 8 June, recruitment to the dexamethasone arm was halted […]
First human trials of new COVID-19 vaccine to begin – Imperial College London
Clinical researchers are this week set to begin human trials of a new coronavirus vaccine developed by researchers at Imperial College London. The study will be the first time the vaccine has been trialled in humans and will test whether it is well-tolerated and produces an effective immune response against COVID-19. Imperial’s vaccine candidate is […]